Adrian's Favorite Slice

Adrian, We're Kneading You — Come Hungry.

Hand-tossed pizza baked to golden perfection and New England–style grinders stacked high with fresh, quality ingredients. Right here on South Main Street, where the ovens are always warm and the doors are always open.

4.8★ Local Favorite
Fresh Daily Ingredients
1416 S. Main St
Freshly baked pizza straight from the oven with melted cheese and crispy crust
Open Tonight 11 AM – 10 PM
Warm interior of Mancino's Pizza Grinders with brick ovens and friendly staff
Close-up of hands tossing pizza dough in the air
Local Adrian
Favorite

Not Just Another Slice.
Adrian's Slice.

Mancino's Pizza Grinders isn't trying to be something we're not. We're a local spot on South Main Street where the pizza is made by hand, the grinders are loaded high, and every person who walks through the door is treated like a regular — even if it's their first time.

Our dough is stretched, not rolled. Our sauce is simmered, not rushed. And our grinders are built the way they should be: on fresh sub rolls, with quality ingredients, and enough cheese to make anyone happy.

Handmade Daily Every crust, every sauce batch, started from scratch.
Community First We're neighbors, not a chain. You matter to us.
No Shortcuts Fresh ingredients, real cheese, and zero shortcuts.

Find Us on
South Main Street

We're right in the heart of Adrian, easy to find and even easier to love. Pull up, walk in, or call ahead — we'll have your food ready.

Address 1416 S Main St
Adrian, MI 49221
Hours Mon – Sun
11:00 AM – 10:00 PM

Ready to Taste the Difference?

Whether you're craving a giant custom pizza, a grinder loaded to the brim, or just a quick bite done right — we're here for you. Call ahead for pickup or just walk in. Your table (or your car trunk) is ready.

Is this your business?This is my business